JAMA Health Forum
The launch of the Advanced Research Projects Agency for Health to advance new cures and address public concern regarding drug prices has raised questions about the roles of government and industry in drug development.
This cross-sectional study examined NIH funding for published research reporting the results of phased clinical trials of drugs approved between 2010 and 2019 and compared the findings with reported industry spending estimates. Data analysis was performed between May 2021 and August 2022 using PubMed data from January 1999 through October 2021 and NIH Research Portfolio Online Reporting Tools Expenditures and Results data from January 1999 through December 2020.
Zhou, Edward W.; Jackson, Matthew J.; and Ledley, Fred D., 2023. Spending on Phased Clinical Development of Approved Drugs by the US National Institutes of Health Compared With Industry, JAMA Health Forum.